WebApr 9, 2024 · We found that 9-month-old female APP/PS1 mice displayed deficits in learning, memory and mood-related behavior, associated with a decreased LTP magnitude in the prefrontal cortex (PFC). Notably, this deficit of PFC-LTP was not associated with the loss of synaptic markers, but instead with decreased levels of the metabolic regulator, sirtuin 1 …
Depression and feeling low - MindWell
WebJun 18, 2024 · Overall, however, the contribution of these variables on mood states was modest (generally less than 5% explained variance by a single variable). Exceptions to this were cognitive/personality characteristics, namely frustration intolerance and neuroticism, which explained up to 20.2% and 15.8%, respectively, of mood states. WebThe psychological symptoms of depression include: continuous low mood or sadness. feeling hopeless and helpless. having low self-esteem. feeling tearful. feeling guilt-ridden. feeling irritable and intolerant of others. having no motivation or interest in things. finding … feeding baby blue birds
Signs of Depression Relapse - WebMD
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