Phospho-4ebp1
WebPhospho-4E-BP1 (Thr37/46) (236B4) Rabbit mAb detects endogenous levels of 4E-BP1 only when phosphorylated at Thr37 and/or Thr46. This antibody may cross-react with 4E-BP2 … Web4EBP1 is a 118 amino acid protein with a predicted molecular weight of 13 kD. Distribution Cytosol and nucleus/ubiquitously expressed Function Regulation of global translation …
Phospho-4ebp1
Did you know?
WebDec 18, 2024 · Scoring of phospho-4EBP1 immunolabeling was performed as follows: each tumor was evaluated in a tissue microarray for positive or negative staining, and assigned a qualitative score based on whether there was low, focal staining (staining in less than 50% of the tumor cells), intermediate staining (weak staining in more than 50% of the cells ...
WebJun 6, 1999 · National Center for Biotechnology Information WebSep 11, 2024 · Glioblastoma is the most common malignant primary brain tumor, and it is one of the causes of cancer fatality in both adult and pediatric populations. Patients with glioblastoma require chemotherapy after surgical resection and radiotherapy. Therefore, chemotherapy constitutes a viable approach for the eradication of glioblastoma cells. In …
WebEIF4EBP1 / 4EBP1 ELISA Kit LS-F1112 is a 96-Well enzyme-linked immunosorbent assay for the Qualitative detection of Human EIF4EBP1 / 4EBP1 in Adherent Cell Cultures. It is a Cell … WebKeyTec®TR-FRET Phospho-STAT4 (Y693) Kit : KeyTec®TR-FRET Phospho-STAT5 (Y694/Y699) Kit : KeyTec®TR-FRET Total STAT5 Kit : KeyTec®TR-FRET Phospho-STAT6 …
WebApr 1, 2024 · We also engineered a mutant 4E-BP1 that cannot be phosphorylated by mTOR resembling de-phospho-Thr46-4E-BP1, and generated HNSCC cells expressing this mutant in a tetracycline-inducible fashion. Expression of 4E-BP1 M was sufficient to disrupt the function of the translation–initiation complex, and resulted in tumor regression in HNSCC ...
Web当你希望让更多商家联系你时，可以勾选后发送询价，平台会将你的询价消息推荐给更多商家。 businesses near frisco txWebJun 24, 2024 · Inhibition of 4EBP1 phosphorylation was sufficient to block cancer cell growth and was necessary for maximal antitumor activity. At mTORC1-selective doses, these compounds do not alter glucose... businesses needed in north dakotaWebJan 2, 2024 · Here we demonstrate that rapamycin-insensitive mTORC1 signaling via 4E-BP1 is a critical pathway for TGF-β 1 stimulated collagen synthesis in human lung fibroblasts, whereas canonical PI3K/Akt... businesses near me that are hiringWebPhospho-4EBP1 (Thr46) Antibody (44-1170G) in ICC/IF Immunofluorescence analysis of 4EBP1 (pT46) was done on 70% confluent log phase HeLa cells. The cells were fixed with 4% paraformaldehyde for 15 minutes, permeabilized with 0.25% Triton™ X-100 for 10 minutes, and blocked with 5% BSA for 1 hour at room temperature. businesses needed in 2018WebJan 9, 2012 · MPTECs were tranduced either with empty vector or NL4-3 and then incubated in media for 72 hours. Subsequently, proteins were extracted from vector/MPTECs and HIV/MPTECs, Western blots were prepared and probed for phospho-70S6K, phospho-eIF4B, and phospho-4EBP1. Immunoblots were stripped and reprobed for actin (n = 4). A. businesses needed in small townsWebThe Phospho-4EBP1 (Thr37/46) assay uses 2 labeled antibodies: one with a donor fluorophore, the other one with an acceptor. The first antibody is selected for its specific … businesses needed in the futureWebOur 4EBP1 polyclonal, monoclonal, recombinant monoclonal and recombinant polyclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by … hands technologies